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- Lectin microarrays could be used for high-throughput screening glycan patterns of therapeutic glycoproteins
Lectin microarrays could be used for high-throughput screening glycan patterns of therapeutic glycoproteins
Glycotechnica’s lectin microarray LecChip™ is an alternative time-effective method, which uses a broad range of lectins for glycan profiling to determine a protein-specific glycan fingerprint. This proof-of-principle study published in 2016, Zhang et al. showed that the lectin-based microarray can effectively distinguish glycans on therapeutic antibodies with high sensitivity, thus offering a simple alternative for rapid glycan profiling of therapeutic glycoproteins.
Now a second lectin array was launched by our partner Glycotechnica which includes 15 Mannose specific lectins. Results are obtained in only 48 hours. Moreover, the lectin microarray allows the identification of N- and O-glycans.
Have a look at the LecChip versions and their specificities: https://buff.ly/3yVLFsK.