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Periostin - A Serum Biomarker for Osteogenesis Imperfecta Progression Osteogenesis Imperfecta (OI), also known as brittle bone disease, is a genetic disorder characterized by fragile bones that break easily, often with little or no apparent cause. It is caused by mutations in the genes responsible for producing collagen, a vital protein for bone strength and [...]

Type 2 Diabetes Mellitus (T2DM) and Cardiovascular (CV) diseases Patients with T2DM have an elevated risk of developing CV diseases due to multiple factors. Chronic hyperglycemia, or elevated blood sugar levels, can cause damage to blood vessels promoting the development of atherosclerosis (1). Insulin resistance, a hallmark of T2DM, contributes to abnormal lipid profiles, such [...]

Monitoring inflammatory responses with serum marker LRG Inflammatory Bowel Diseases (IBD) are chronic conditions characterized by inflammation of the gastrointestinal tract. The main types are Crohn's disease and ulcerative colitis. Crohn's can affect any part of the digestive tract and involves all layers of the intestinal wall, while ulcerative colitis primarily affects the colon and [...]