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Join us at ECTS
We are excited to be soon attending the ECTS Congress in Innsbruck, Austria from May 23-26, 2025. Meet us at our banner exhibition “Biomedica´s Bone Marker ELISAs” and explore our kits including SCLEROSTIN, OPG, RANKL, FGF23, PERIOSTIN, and many others.
We look forward to connecting with you!
Join us at ECTS
Click here for more information about the congress.
The ECTS 2025 Congress is recognized as the premier annual gathering in Europe dedicated to this field. The congress offers a comprehensive and engaging scientific program that covers the most recent advances, challenges, and debates related to bone and calcified tissues. The program aims to unite researchers, clinicians, and health professionals, showcasing their latest research.
Biomarkers in Bone Biology
Bone cells produce biomarkers throughout the process of bone remodeling. These biomarkers are valuable for evaluating bone diseases and serve as potential therapeutic targets. They can be readily identified in serum and plasma samples using immunoassay techniques.
A recent review by Fernández-Villabrille S et al., Novel Biomarkers of Bone Metabolism explores some emerging biomarkers in mineral and bone metabolism like:
Receptor Activator of NFkappa B lingand (RANKL), Osteoprotegerin (OPG), Sclerostin (SOST), Dickkopf-1 (DKK-1), Periostin (POSTN) and others.
BIOMEDICA offers quality Bone Marker ELISA assay kits:
-Sclerostin ELISA (SOST; cat.no. BI-20492)
-OPG ELISA (Osteoprotegerin; cat.no. BI-20403)
-RANKL ELISA (soluble RANKL; cat.no. BI-20462)
-DKK-1 ELISA (Dickkopf-1; cat.no. BI-20413)
-FGF23 intact ELISA (Fibroblast growth factor-23 intact; cat.no. BI-20700)
-FGF23 C-terminal ELISA (Fibroblast growth factor-23 C-terminal; cat.no. cat.no. BI-20702)
-PERIOSTIN ELISA (POSTN, BI-20433)
-NT-proCNP ELISA (NT-C-type natriuretic peptide, BI-20812)
TRUSTED – cited in over 1300 publications
- Kit validations follows international quality guidelines
- Developed & manufactured by Biomedica in Austria
About SCLEROSTIN
Sclerostin (SOST), primarily produced by osteocytes, is regarded as a key regulator of bone formation. It functions as a soluble antagonist of the Wnt signaling pathway. Inhibition of this pathway results in bone resorption, whereas activation of Wnt signaling stimulates bone formation.
About PERIOSTIN
Periostin (POSTN) is an extracellular matrix protein predominantly expressed in the periosteum, the membrane covering the outer surface of bones that plays a role in bone growth. It is involved in various processes, including bone biology, tissue repair, cancer, cardiovascular and respiratory conditions, as well as in numerous inflammatory conditions such as asthma.