Quality IL-6 ELISA Kit - Cost-Effective and Efficient

Quality IL-6 ELISA Kit – Cost-Effective and Efficient for Your Research!

Interleukin-6 (IL-6) is a multifunctional cytokine involved in regulating immune responses, inflammation, and hematopoiesis (1). It is produced by numerous cell types, including T cells, B cells, macrophages, and fibroblasts. IL-6 plays a crucial role in mediating the body’s response to infections and tissue damage. It promotes the activation of immune cells, stimulates the production of acute-phase proteins, and influences metabolic and regenerative processes (1). Elevated levels of IL-6 are associated with chronic inflammatory diseases, autoimmune disorders, and certain cancers, making it an important biomarker for disease diagnosis and monitoring. Due to its pivotal role in immune regulation, IL-6 is a key target for therapeutic interventions in inflammatory conditions.

In addition to its general functions, IL-6 is implicated in the pathogenesis of several diseases. In cardiovascular diseases (CVD), elevated IL-6 levels contribute to atherosclerosis by promoting inflammation within arterial walls, leading to plaque formation and instability, which can result in heart attacks and strokes. Additionally, elevated IL-6 levels, commonly detected in various neurodegenerative disorders, suggest its potential utility as a biomarker for disease progression and prognosis (3, 4).

Discover BIOMEDICA´s Quality Human Interleukin-6 (IL-6) ELISA Kit (cat. no. BI-IL6)

developed and manufactured by Biomedica

• SENSITIVE – detects IL-6 in serum and plasma samples
• HIGHLY SPECIFIC – characterized recombinant epitope-mapped antibodies
• STANDARDIZED – calibrated with WHO standards for accuracy
• QUALITY ASSURED – validated in accordance with international guidelines
• USER-FRIENDLY – includes ready-to-use, color-coded, prediluted standards and controls 

 

Elevate your research with reliable and easy-to-use IL-6 detection!

Biomedica´s Human IL-6 ELISA ASSAY CHARACTERISTICS (#BI-IL6)

-Method: Sandwich ELISA using HRP/TMB detection with 12×8-well detachable strips 

-Sample types: Plasma (EDTA, citrate, heparin), serum, cell culture, urine 

-Sample volume per well: 100 µl 

-Incubation times: 2 hours / 1 hour / 1 hour / 30 minutes 

-Sensitivity: 0.28 pg/ml (LLOQ: 0.78 pg/ml; capable of measuring concentrations in serum and plasma samples) 

-Assay range: 0 – 200 pg/ml, with standard concentrations at 0 / 3.12 / 6.25 / 12.5 / 25 / 50 / 100 / 200 pg/ml 

-Precision: Intra-assay CV ≤ 6%; Inter-assay CV ≤ 7% (n=3) 

-Specificity: Recognizes both recombinant and endogenous human IL-6 

-Validation data: Includes assessments of precision, accuracy, dilution linearity, and parallelism; healthy donor values are provided

-Use: For research purposes only

Quality IL-6 ELISA Kit – Cost-Effective and Efficient for Your Research!

 

 

Literature

1. IL-6 in inflammation, immunity, and disease. Tanaka T, Narazaki M, Kishimoto T. Cold Spring Harb Perspect Biol. 2014 Sep 4;6(10):a016295. doi: 10.1101/cshperspect.a016295. PMID: 25190079; PMCID: PMC4176007.
2. IL-6 in the spotlight: From cardiovascular pathophysiology to therapy. Preda A, Tirandi A, Leo G, Di Vece D, Vilahur G, Bonaventura A, Osto E, Ministrini S, Kraler S, Kleinbogard P, Camici G, Carbone F, Montecucco F, Liberale L.Eur J Clin Invest. 2026 Jan;56(1):e70161. doi: 10.1111/eci.70161. Epub 2025 Dec 3. PMID: 41340186.
3. The Role of IL-6 in Neurodegenerative Disorders. Shan C, Zhang C, Zhang C. Neurochem Res. 2024 Apr;49(4):834-846. doi: 10.1007/s11064-023-04085-6. Epub 2024 Jan 16. PMID: 38227113.
4. IL-6, IL-8 and IL-10 polymorphisms may impact predisposition of Alzheimer’s disease: a meta-analysis. Yang R, Duan J, Luo F, Tao P, Hu C.Acta Neurol Belg. 2021 Dec;121(6):1505-1512. doi: 10.1007/s13760-020-01369-4. Epub 2020 May 12. PMID: 32399737.