Vanin 1 and kidney disease
Vanin-1 is a glycoprotein which is selectively expressed in renal tubular cells.
As a biomarker urinary Vanin-1 has shown superior value in the prediction of drug induced acute kidney injury compared to the established markers KIM-1 or NGAL. It can also help in the detection and monitoring of obstructive nephropathy.
At Biomedica we offer the FIRST fully validated VANIN-1 (urine) ELISA. Our quick, one-step ELISA is optimized for human urine samples and rigorously validated according to FDA/ICH/EMEA guidelines.
For more information see:
Urinary Vanin-1 As a Novel Biomarker for Early Detection of Drug-Induced Acute Kidney Injury
Hosohata K et al., J Pharmoc Exp Therapeut, 2012
A Novel Biomarker for Acute Kidney Injury, Vanin-1, for Obstructive Nephropathy: A Prospective Cohort Pilot Study
Washino S. et al., Int J Mol Sci, 2019