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  • Altered Concentrations of DKK1 and FGF23 in WNT1 and PLS3 Osteoporosis
    28 July, 2020
    Recent advancements in genetic #research have uncovered new forms of monogenic #osteoporosis. Mutations in WNT1, encoding a WNT/β-catenin pathway ligand WNT1, and PLS3, encoding X chromosomally inherited plastin 3 (PLS3), both result in early-onset osteoporosis with prevalent fractures and disrupted bone metabolism. Data from a study by Mäkitie RE et al. indicate a link between [...]
  • Big Endothelin-1 level is an independent predictor of long-term mortality in patients with three-vessel disease.
    9 July, 2020
    Endothelin-1 (ET-1) is a potent vasoconstrictor secreted by vascular endothelial cells. Due to its high biologic activity, ET-1 is rapidly cleared. However, big ET-1, the precursor of ET-1, has a much longer half-life, circulates in higher concentrations and is easier to detect. Thus, big-ET-1 is a more suitable marker and can be used as an [...]
  • Soluble RANKL promotes the formation of tumour metastasis in bone.
    9 June, 2020
    Soluble RANKL is physiologically dispensable but accelerates tumour metastasis to bone.Asano T. et al., Nat. Metab. 2019, 1: 868–875. Data from a study by Asano et al. suggest that membrane-bound RANKL is sufficient for most physiological RANKL functions. By contrast, soluble RANKL specifically contributes to bone metastasis by exerting a chemotactic activity in tumour cells [...]
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Events
  • Biomedica @ Osteologie 2020 in Salzburg
    17 February, 2020
    Meet us at the Osteologie 2020, hosted by the Deutsche Gesellschaft für Endokrinologie and the Österreichische Gesellschaft für Knochen- und Mineralstoffwechsel, taking place from 12-14 March 2020 in Salzburg, Austria! We will exhibit together with our partners Fianostics & TAmiRNA at booth #1. Moreover,  we will present out new VEGF-A ELISA at our poster "Novel VEGF-A ELISA [...]
  • Biomedica @ ASN
    7 November, 2019
    Meet us during ASN Kidney Week taking place from November 5-10 2019 in Washington, DC at booth no. 2005 Hosted by the American Society of Nephrology it’s the world’s premier nephrology meeting with more than 13,000 kidney specialists from across the globe. It provides participants with exciting and challenging opportunities to exchange knowledge, learn about [...]
  • Biomedica @ ASMBR
    18 September, 2019
    Meet us at the ASBMR in Orlando at The Biomedica booth # 516 Our Posters: #SUN-103, #SUN-271, #MON-252 and #MON-331 Tje Bone Turnover Markers Working Group Room# W307B, Sept 20 at 7:30pm Diurnal Changes in Serum Levels of Bone-Related Circulating MicroRNAs. Oral presentation #1140, room# W314, Monday, Sept 23 from 2:15pm-2:30pm If you cannot make it to the ASBMR [...]
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